Already up 6-0 entering the top of the sixth in Kansas City, Corey Koskie leads off the inning with a single. Ron Coomer, Jacque Jones, and Matt LeCroy then proceed to hit three consecutive home runs on four total pitches. Coomer homered again in the seventh, again with Koskie on base.
Eric Milton retired the first 20 batters in order and had a two-hit shutout going into the eighth. After retiring the first two batters, including former Twin David McCarty, Milton allowed two hits before being relieved by Eddie Guardado. Guardado gave up an RBI single and then back-to-back home runs to Carlos Beltran and Jermaine Dye before being relieved by Hector Carrasco who surrendered the Royals’ third consecutive home run to Mike Sweeney. It was the first game in major league history in which both teams hit back-to-back-to-back home runs.
The Twins are one of seven teams to have hit four consecutive home runs, with Tony Oliva, Bob Allison, Jimmie Hall, and Harmon Killebrew doing so to start the top of the 11th in Kansas City on May 2, 1964.
The Twins set an American League record by hitting five home runs in a single inning on June 9, 1966, also against Kansas City, but this time at home in Bloomington, with Rich Rollins, Zoilo Versalles, Tony Oliva, Don Mincher, and Harmon Killebrew homering off three different Athletics pitchers.
Four National League teams have hit five home runs in an inning between 1939 and 2006, all four against the Cincinnati Reds.